Microdialysis Experts

Microdialysis Experts is a consulting service. We will design your drug discovery project by using in vivo microdialysis:

• For the drug efficacy study;

• For the biophase pharmacokinetic study;
  

• For the drug BBB penetration study;

• For evaluation of PK/PD relationship of drug and its metabolites. See our experts opining

Our expertise also included: LC-MS/MS method development for      pharmacokinetic study of biological therapeutics (peptide and small protein <20K). We could use LC-MS/MS method measuring Peptide in plasma at pg/ml level. See our poster.

We also help you with:

• Set up your microdialysis collection system; Instruct you in microdialysis surgery; Provide training in collecting microdialysis samples.
• Provide training and trouble shooting different analytical instruments for sample analysis which included:
• high performance liquid chromatograph-electrochemical detection (HPLC-ED),
• Capillary electrophoresis-laser induced fluorescence detection (CE-LIF),
• Specially liquid chromatograph tandem mass spectrometry (LC/MS/MS) which could analysis biomarkers (neurotransmitters or neuropeptides) and drug in single microdialysis sample.
• Answer microdialysis related question for graduate student and postdoctoral fellow.